Shibata 21_6
نویسندگان
چکیده
To investigate the effects of fermented brown rice (FBRA) on the development of hereditary hepatitis in LongEvans Cinnamon (LEC) rats, we compared the incidence and grades of acute hepatitis among rats fed 5% and 10% FBRA in the conventional diet and the conventional diet alone. Both the 5% and 10% FBRA-supplemented diets indicated a tendency to prevent the development of hepatitis, and the significant effect of 10% FBRA was observed until 16-17 weeks of age in the accumulated incidence and survival ratio compared with the unsupplemented conventional diet, although no significant difference was observed between 5% and 10% FBRA-supplemented diets. At the age of 12 weeks, which is just before the rats develop hepatitis, serum copper levels in rats fed either of the test diets were similar to those in rats fed the conventional diet. Furthermore, the copper concentration in liver tissue at 12 weeks of age was not changed by the test diet. These results suggest that FBRA has preventive effects on the development of hepatitis in LEC rats and may play an important role in protecting the liver against the free radicals induced by copper accumulation in the liver.
منابع مشابه
1 15 - Deoxy - 12 , 14 - prostaglandin J 2 : A prostaglandin D 2 metabolite generated during inflammatory processes
متن کامل
Incidence of stroke in Shibata, Japan: 1976-1978.
A stroke registry was established in Shibata City, Niigata Prefecture, Japan (population 75,000) in 1976. WHO recommendations for criteria were followed. This paper reports stroke incidence for the initial 3 years of the registry: 1976 through 1978. All living patients were examined clinically by a staff physician. Only patients with a diagnosis of first stroke were included in the study. Sensi...
متن کاملA Directional - Edge - Based Face Detection Algorithm Adapted to the VLSI Image Recognition System
There has been a considerable interest in the development of human-like image perception systems. Although a number of algorithms have been proposed so far, it is still a challenging task to achieve a human-like robustness in image perception under various circumstances. For robust image perception, the feature representation algorithm which extracts essential features from an image and represe...
متن کاملDefibrillators and ventricular dysfunction.
2. Ragsdale BD: Anitschkow nuclear structure in cardiac metastases. Am J Clin Pathol 1973;59:798-802 3. Masani F, Iwanaga T, Shibata A, Fujita T: Immunohistochemical demonstration of S-100 protein in fibroblast-like cells of the guineapig heart. Arch Histol Jpn 1986;49:117-127 4. Kodama M, Zhang S, Hanawa H, Shibata A: Immunohistochemical characterization of infiltrating mononuclear cells in th...
متن کاملMultiple Interior Layers of Solutions to Perturbed Elliptic Sine–gordon Equation on an Interval
We consider the perturbed elliptic Sine–Gordon ODE with two positive parameters μ and λ, and show the existence of solutions which have 2n multiple interior layers for λ 1. We also determine the location of multiple interior layers as λ→∞.
متن کامل